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Although it has not been approved by the fda for use by pregnant women in combating pregnancy-related nausea, zofran has been prescribed by many doctors as an off-label treatment for morning sickness.
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Usually, the symptoms respond to an anti motion-sickness drug such as meclizine antivert, bonine, or dramamine ; , the newer skin patches that deliver scopolamine, or the anti-nausea drug ondansetron zofran ;.
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In an active-controlled, double-blind trial in 105 patients receiving single high-dose radiotherapy 800 to 1,000 cgy over an anterior or posterior field size of greater than or equal to 80 cm 2 to the abdomen, zofran was significantly more effective than metoclopramide with respect to complete control of emesis 0 emetic episodes .
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